Posted on by Karin A Crowhurst

The Abrol lab has published a collaborative research article with a Japanese group

The Abrol lab has published a paper with Inoue lab at Tohoku University in Japan, with significant contributions by former CSUN student Christian Cruz (BS Biochem). The article, titled “Identification of Gα12-vs-Gα13-coupling determinants and development of a Gα12/13-coupled designer GPCR” is published in the journal Scientific Reports. The above figure summarizes the computational modeling part of the paper that not only helped explain our collaborator’s observations of G12 selectivity of a designer receptor but also contributed to the design of a new designer receptor.

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